Primary Sclerosing Cholangitis

Primary sclerosing cholangitis. Detail of portal tract with moderately dense inflammatory infiltrate (mainly lymphocytes, some eosinophils) and concentric, lamellated, periductal fibrosis (‘onion skin’ fibrosis) around the interlobular bile duct (center). (H&E)

Primary sclerosing cholangitis. Detail of portal tract with moderately dense inflammatory infiltrate (mainly lymphocytes, some eosinophils) and concentric, lamellated, periductal fibrosis (‘onion skin’ fibrosis) around the interlobular bile duct (center). (H&E)

Source: Rosai: Surgical Pathology 9th edition